But Villaraigosa told NBC 4 in L.A. that the two are not Cabo bros.
"I had a three-minute conversation, I took a picture with him," Mayor Villaraigosa told a local NBC station.
"I have never said no to anyone who wanted to take a picture," the mayor added.
Sheen refuted Villaraigosa's story, telling TMZ, "I memorize 95 pages a week, so the last thing that I am is memory challenged. We hung out for the better part of 2 hours, discussing his L.A. roots, his poignant bullet campaign as well as his 3 AM lawn-watering tactics."
He also said the two had a "memorable night" together, drinking in a suite with a group of women that included "at least one porn star."