The meeting with survivors from Britain, Ireland, Poland, and the United States will be private.
Those in attendance will have the opportunity to speak one-on-one with the head of the Catholic Church.
His audience with those who have experienced sexual abuse will coincide with the second meeting of the Pontifical Council for the Protection of Minors, convened to advise Pope Francis on the Church's measures to protect children.
The Holy Father has promised a "zero tolerance" approach to clergy abuse.
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