More than 1,000 homes were damaged and 17 were completely destroyed by the temblor, which occurred at 5:27 p.m. local time.
The epicenter was located at a depth of 8.1 miles, about 6 miles west of Valle San Francisco and 23 miles east-northeast of La Paz Centro. There were at least 350 aftershocks following the main event, registering between 3.5- and 5.0-magnitude.
Nicaraguan President Daniel Ortega put the region on red alert and school was canceled Friday in Managua and Leon.
Notable deaths of 2014 [PHOTOS]
Yemeni prime minister resigns amid fighting