If successful, Bossi, who resigned last year under the cloud of a corruption scandal, would replace Roberto Maroni, governor of the Lombardy region in northern Italian region, ANSA reported.
"I'm glad he's running," Maroni said. "Anyone can participate. No games this time -- the secretary is getting elected by the rank and file."
Bossi led the Northern League until a corruption scandal over the alleged channeling of millions of dollars of public monies into private accounts forced him out last year.