Nepalnews.com, quoting family members, reported Ghimire had been in stable condition for some time but was admitted to a Kathmandu hospital after his condition suddenly worsened. The report said doctors pronounced him dead early Thursday.
Ghimire was the author of eight books, which included his autobiography "Antarmanko Yatra" (A Journey Within), which won him the Madan Puraskar, the Himalayan state's prestigious literary award. The book also won other honors. His other books were novels, the report said.
As a social worker, Ghimire co-founded the Tamakoshi Seva Samiti, a non-profit group devoted to women's empowerment, sustainable agriculture and providing access to safe drinking water. He was also the founder of the Tilganga Eye Hospital.
Ghimire is survived by his wife and two children.