The Henna was ordered to remain in port on Jeju Island amid a legal dispute between HNA Cruise and another Chinese company.
The first 450 passengers boarded an airliner in Jeju for the flight home. The Henna carried 1,659 passengers and 650 crew.
China's Xinhua News Agency said the vessel was scheduled to sail from Jeju to Incheon but a Korean court ordered it to remain in port.
China's National Tourism Administration Saturday called on South Korea to immediately lift the detention order to allow the ship to sail as soon as possible.