The firings, transfers and prosecutions involved explosions at a coal mine and a fire at a poultry processing plant, which caused a combined total of 174 deaths.
The State Council said in a written statement this weekend the punishments included the arrest of 35 people, including executives of the companies and government officials in Jilin province.
The province in northeastern China was the scene of two blasts that struck the Babao Coal Mine on March 29 and April 1, killing 53 and injuring 20. In June, fire at the Jilin Baoyuanfeng Poultry Company caused 121 deaths and 76 injuries.
China's Xinhua news agency said Sunday the investigation concluded that lax safety standards were the primary contributor to both disasters. The council ordered all industry in Jilin to conduct safety checks of its plants and other facilities.