The arrests Friday were made during a racketeering and drug-trafficking investigation into the Camorra Mafia, ANSA reported.
Members of the Marfella family, described by police as Mafia leaders, were among those arrested.
Police seized the assets from Carlo Sama, a waste-management entrepreneur with ties to the Calabrian 'Ndrangheta Mafia, ANSA said.
Authorities froze six of the Sama's bank accounts and confiscated some property.
In Palermo, officials said they plan to continue an investigation into suspected Mafia links by Senate Whip Renato Schifani of Silvio Berlusconi's People of Freedom (PdL) Party, ANSA said.
Schifani is accused of meeting with Cosa Nostra boss Filippo Graviano while he was a lawyer in Palermo in the 1980s.