Madrid, Mancha and Navarra are among the hardest hit regions, thinkSPAIN reported, and areas in the south have already been hit hard or will be soon.
In areas in the western region of Galicia, snow in remote areas has reached as much as 5 feet deep.
On average, the snow is not higher than 6 inches, thinkSPAIN said.
Meteorologists said snow is expected to hit all areas that are sea-level or higher, accompanied by winds as high as 60 mph.
ThinkSPAIN said the cold weather is expected to stay until at least mid-week.