A suicide car bomb intended for a NATO convoy in Kapisa province killed five civilians and injured at least 15, Khaama Press reported.
The bomber detonated the explosives in front of a home in a residential area of Jalo Khel in the Tagab district, said deputy provincial governor Aziz-ur-Rahman Tawab.
The Afghan Ministry of Interior said the five dead included four members of one family, the Los Angeles Times reported.
In a text message to journalists, the Taliban took responsibility for the blast, claiming 12 American soldiers were killed or injured and two tanks destroyed.
NATO said there were no reports of casualties among the forces in the convoy.
Three Georgian soldiers were injured in a separate attack, Khaama Press reported.
Georgian defense officials said militants opened fire while the troops were on patrol.
Two of the men were in stable condition with minor injuries, the officials said. A third soldier was seriously wounded by an anti-personnel mine.
The exact location of the incident was not disclosed.