At least 20 of the train's 60 cars derailed after the train collided with a single locomotive that was on the same track, RIA Novosti reported.
"According to initial information, the locomotive crew of two have been killed -- the driver and his assistant," the local Emergencies Ministry said.
Traffic along the train line was stopped, causing delays for a passenger train traveling from Novosibirsk to Vladivostok.
"Food and hot water have been supplied to [the passenger train]," the Emergency Ministry said.
Celebrity Breakups and divorces of 2014 [PHOTOS]