Bashir Ahmed Bilour died in surgery after a bomber detonated a device in Peshawar in northwest Pakistan.
The blast occurred near the site of a meeting of the Awami National Party and killed Bilour's personal secretary and a police officer, Dawn News said. Another 18 victims were injured.
Bilour was a senior leader of the ANP, which Dawn said was the largest and current ruling political party in Khyber Pakhtunkhwa province.
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