A house was targeted in the Hisukhel area of Mir Ali -- about 15.5 miles east of Miramshah, the main town in North Waziristan, Dawn News reported.
Four militants inside the house were killed, an intelligence official said.
It was not know if the victims were affiliated with a specific group.
The News International reported that officials said another U.S. drone crashed in an uninhabited area of South Waziristan.
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