Tunisia representatives said they hope to raise more than $13 million from the auction.
Middle East Online said the highlight of the auction is the former president's cars, which include a Lamborghini Gallardo LP 460.
Middle East Online said 300 jewelry items, carpets, tables, televisions and computers will be put up for sale at a hotel in Gammarth, a suburb of Tunis.
Acting Finance Minister Slim Besbes said the items belonged to Ben Ali and 114 of his relatives.
"Except [citizens] of Israel, the sale is open to everyone," Besbes said.
Besbes said the auction will be held under tight security and $20 will be charged for entry.
Middle East Online said Ben Ali now lives in exile in Saudi Arabia with his wife after fleeing during the uprisings last year.