China's Xinhua News Agency said more than 100 other injuries were reported in Singu, located in northern Myanmar. At least five aftershocks were felt, local experts told the news agency.
A man was killed when a brick wall of a restaurant collapsed, an information official said. In the township of Sint Ku, a gold mine, a monastery and a house collapsed, killing six people, CNN reported.
The five missing workers had been on a bridge under construction that collapsed into the river.
Xinhua said pagodas, residential houses and school buildings also collapsed in Shwebo, Singu, Mandalay and Tabaitgine.
The quake began about 7:40 a.m. local time at a depth of about 12 miles. The U.S. Geological Survey reported it was centered 32 miles north-northeast of the town of Shwebo in the Sagaing region.