The suspects, all Londoners in their 20s, were in a vehicle that was stopped by officers from the Civil Nuclear Constabulary that guards the Sellafield nuclear site in Northwest England, The Guardian of Britain reported Tuesday.
Sellafield is responsible for decommissioning and reprocessing nuclear waste and manufacturing fuel.
The five suspects were arrested Monday afternoon and held overnight in Carlisle before being moved to Manchester Tuesday morning.
The men were thought to be filming near the nuclear site and all five were Bangladeshis, the BBC reported.
Greater Manchester police said the investigation is in its early stages.
They said they were not aware of any connection between the arrests and Sunday's death of Osama bin Laden by U.S. SEALs.