Malcolm Webster, 51, of Guilford near London is charged with murder and fraud, the Daily Mail reported. The trial in Glasgow High Court got under way Tuesday and is expected to last four months.
Webster's first wife, Claire Morris, also a nurse, was found dead in a burned-out car near Aberdeen in 1994. Prosecutors charge Webster drugged her, pushed the car down an embankment and set it on fire.
Five years later, in New Zealand, his second wife, Felicity Drumm, survived a crash into a tree, prosecutors said as they laid out their case. They charge he made several attempts on her life in several countries.
Both wives were heavily insured.
In an additional twist, Webster allegedly courted a third woman, Simone Banarjee, in Oban, Scotland, while still legally married to Drumm. He allegedly told her falsely he was dying of leukemia, and tried to convince her to marry him and leave him her entire estate.
Webster denies all charges.