Clinton beat each of the Republicans' likely candidates, with the closest, Florida Senator Marco Rubio and Wisconsin Congressman Paul Ryan, trailing Clinton by 7 points. She also polled better than New Jersey Governor Chris Christie, who confirmed Wednesday that he is considering a run for the White House.
Most striking is the lead she has over controversial Texas Senator Ted Cruz. If the election were held today between Clinton and Cruz, the former Secretary of State would trounce the man many see as the leader of the Tea Party, with 51 percent going for Clinton and only 37 percent for Cruz.
Clinton has a history of success in Ohio, beating President Obama in the state's 2008 Democratic primary. The poll, however, notes that Obama's struggling approval rating -- just 39 percent in the Rustbelt's bellwether state -- could harm Clinton with Ohio voters.
"President Barack Obama's job approval remains stuck at about 40 percent in Ohio," the study says. "Although he is not on the ballot this November, such a consistently low rating can't be helpful to the Democratic ticket."
The poll also included popular Ohio Governor John Kasich. Kasich, who once led a campaign to ban the movie Fargo for not being funny enough to be called a comedy, would lose to Clinton by five points.