The eaglet was the first of three eggs waiting to be hatched in the nest in the Hays section of Pittsburgh, near the Monongahela River, WTAE-TV, Pittsburgh reported.
"Generally, the first eaglet that hatches will have the best chance. The mortality rate can be as high as 50 percent within the first year," said Pennsylvania Game Commissioner Officer Gary Fujak.
Fujak said the second egg would likely be hatched within three days of the first and the last egg three days later.
"This is great. It is showing how adaptive wildlife is and how resilient they are," he said.
A 24-hour live video feed of the nest is available to watch online.