"There may be reasons I don't run, but there's no obvious reason for me why I think I should not run," he said on CNN's "New Day."
A decision would be made "realistically, a year this summer," Biden said.
Biden, 71, sought to be the democratic presidential nominee in 2008, when then Sen. Barack Obama was the party's standard-bearer.
Members of Congress to keep receiving porn magazine
Disney's 'Jessie' to feature network's first engagement