The crash occurred at Southwest 100 Street and Krome Avenue, WBFS-TV, Miami, reported.
The TV station said the van driver said he tried to brake to avoid a car in front of him and served to the left, colliding with the motorcycles. One of the bikes caught fire.
The victims were taken to area hospitals. The extent of their injuries wasn't known.
Pistorius testifies he didn't consciously pull trigger when he shot girlfriend
Google buys drone maker Titan Aerospace