Cruz declined to comment on his own presidential aspirations, but he told CNN's "State of the Union" that conservative Republicans were in good position to oust the Democrats from control if the U.S. Senate.
"I think it is likely that I'll stay out of all incumbent races," Cruz said. "I intend to be very involved in 2014 in open seats and working to help support strong conservative candidates. I think 2014 is a very favorable environment for Republicans to retake the Senate."
Cruz said his optimism about the GOP's fortunes is based on the increasing clout of conservative grassroots groups that have waged a no-prisoners war against President Obama's healthcare reforms.
Cruz said conservatives and business groups had drawn a line in the sand against the reviled Obamacare and have show little interest in working with the system as it takes effect.
"I think now is the single best time to stop Obamacare, because there's bipartisan agreement that it's not working," Cruz said.