"Our laws should protect victims. Not create more. Stand up to stand your ground laws in 26 states," appears on the screen in the video, which was created by the Coalition to Stop Gun Violence.
The video, which was released Monday, also uses real 911 recordings made by George Zimmerman from the night he shot Martin, 17, in Sanford, Fla.
Zimmerman's call to a police dispatcher is heard, as well as a call from one of his female neighbors.
Screams and a gunshot are heard in the background, the Orlando Sentinel said.
In reference to Martin wearing a hoodie the night he was killed, the video ends with young men wearing hoodies lying on the ground.
Next to them are the names of states that have "stand your ground laws."
A jury found Zimmerman not guilty in July. He had been charged with second-degree murder.