The newspaper reported Thursday that one source said Gotti, 70, suffered her third stroke since 2006 last week and another source said it was a very serious episode.
The Daily News said Gotti's daughter, Linda Gotti, could not be reached for comment Wednesday.
Producer Marc Fiore, who has been involved in a film project about the life of Gotti's son, John Gotti Jr., declined to comment, saying he is not a family spokesman.
"This is a personal family crisis," Fiore said.
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