The blaze destroyed the house in Newman Friday night, but not before a passerby pulled a 10-year-old girl to safety.
Police Chief Douglas Meadows told CNN the adult victim, 28-year-old Alonna McCrary, was the mother of two of the kids. All of the children, however, were related.
The children were all under the age of 5. The cause of the fire was under investigation Saturday.
Notable deaths of 2014 [PHOTOS]