The Philadelphia Inquirer said Christina Regusters would be charged with kidnapping, rape, conspiracy and aggravated assault.
Regusters worked at an after-school program the victim attended at Bryant Elementary and allegedly dressed herself in full-length, face-covering Muslim clothing to pose as the girl's mother and pick her up from school, the report said.
The day after she disappeared, the girl was found half-clothed at a playground, investigators said Thursday.
The 5-year-old showed police the home where she was taken.
Police said they were questioning three other people in the case.