JetBlue Airways corporate communications spokeswoman Sharon Jones told NBC-TV, San Diego, Flight 185 from JFK to the San Diego International Airport landed in Denver at 7:15 p.m.
The 137 people on board deplaned safely and the "unruly customer" was met by police, Jones said. The passenger's name was not reported, and the airline did not provide details about the incident.
FAA spokesman Ian Gregor said the diversion was caused by a "security issue" but did not elaborate.
FBI officials told the station the disturbance was unrelated to terrorism.
The FBI and the Transportation Security Administration were taking over the investigation, the TV station said.