The comment came just days after a super PAC promoting a 2016 Clinton presidential run was registered with the Federal Election Commission.
During a question-and-answer session with an international group of students at the Newseum in Washington, Clinton said she is "not thinking about anything like that right now," but does plan to write a memoir and work on issues important to her, The Washington Post reported.
"I am looking forward to finishing up my tenure as secretary of state and then catching up on about 20 years of sleep deprivation," said Clinton, who will leave the State Department Friday.
Clinton -- a former U.S. first lady and Democratic U.S. senator from New York -- said her interest in seeing more women get involved in top leadership positions includes a desire "to see more women compete for the highest positions in their countries."
"I will do what I can, whether or not it is up to me to make a decision on my own future -- I right now am not inclined to do that -- but I will do everything I can to make sure that women compete at the highest levels not only in the United States, but around the world."
The Ready for Hillary super PAC, led by Allida Black, founder of the Eleanor Roosevelt Papers Project at George Washington University, who also was behind the pro-Clinton political action committee WomenCount, was registered with the FEC Friday.
"Our purpose is simple: We are ready to work for Hillary to be president when she is ready to run," Black told the Center for Public Integrity, which first discovered the filing. "When our website launches in a few weeks, we plan to reach out to our grassroots networks and contributors to mobilize them to support her."
The PAC's Facebook page describes Ready for Hillary as "an idea 5 long time friends came up with: one a former aide to Hillary, one a former adviser to Hillary, one a social media guru, and 2 local Democratic activists. The goal? Get Ready for Hillary!"
Polls indicate Clinton is a front-runner for the Democratic presidential nomination in 2016.