Napolitano had planned to stay and the administration confirmed her decision Monday while Vilsack issued a statement on his intentions, The Washington Post reported.
"President Obama and I share a deep appreciation for rural America and its unlimited potential in the years ahead to feed a growing world population," Vilsack said in his statement issued Monday.
Vilsack, a former governor of Iowa and Obama's chief representative to rural Americans, could play a key role as the administration begins its campaign to modify gun laws, the Post said.
Napolitano, a former governor of Arizona, could play an important role in Obama's drive for immigration reform legislation, which the administration has said is a top priority.
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