At least 20 vehicles were involved in the crashes around 7 a.m., the Chicago Tribune reported.
One crash in the northbound lanes of I-65 near mile post 227 involved 12 vehicles, killing one person and injuring six others, Indiana State Police Sgt. Dan Leslie said.
A second crash involving six vehicles and a third crash involving two vehicles in the southbound lanes left three people with non-life-threatening injuries, the newspaper said.
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