The Detroit Free Press reported Crystal Spencer, 33, of Farmington Hills, died Sunday, her husband, Jeff Spencer, said.
She had been hospitalized since June 30. Her family believes she contracted the disease while having a boil lanced at a medical center, the report said.
Spencer had undergone multiple surgeries, including skin grafts, to areas destroyed by the bacteria. Her recovery was complicated by a diabetic condition.
Many types of bacteria can cause the disease, known as necrotizing fasciitis.