The shark attack happened around 4 p.m. Wednesday, at a beach just south of the New Smyrna Beach jetty, the Orlando (Fla.) Sentinel reported.
Beach Patrol Capt. Tamara Marris said a girl, 15, was bitten on her ankle and a boy, 17, on his calf.
Both were taken to a hospital and treated for non-life-threatening wounds, Marris said.
Marris said the two teens were not at the beach together and that they were in waist-deep water when attacked.
Beach Patrol officers cleared people in the area from the water after the attack, said Marris.
Beyonce flaunts bikini body, Blue Ivy in vacation pics
Couple mistakenly served bag of cash at McDonald's drive-thru