In an interview Wednesday on MSNBC's "Morning Joe," Heilemann said he thinks there is a "99.4" percent chance the secretary of state will run for president. Halperin said he thinks the odds are slightly lower, Politico reported.
"I think that if Joe Biden wins re-election [as vice president] and runs, she's much less likely to run."
The prediction was made during a discussion about a column in The New York Times that says Clinton's run for president may be inevitable.
"Women who assumed that electing Obama would lift all minority boats are beginning to think: Maybe he's not enough," columnist Maureen Dowd wrote.
Clinton has said she has no interest in running for president in 2016.