The fire began around 6 a.m. Tuesday at the Goslin Nix Stables in Magnolia, KHOU-TV, Houston, reported.
Firefighters were able to free 14 other horses from the 5,000 square foot stable.
Some of the surviving horses suffered burns and smoke inhalation, but all were expected to live.
Firefighters from Montgomery County, Magnolia, The Woodlands and Needham volunteer fire departments battled the fire that destroyed the stable and killed 14 horses, each of which are valued between $60,000 and $100,000.
The cause of the fire is under investigation.