The Increasing Faith International Ministries church in Decatur, Ga., was a wreck after the overnight rampage, with computers and musical instruments destroyed, the pulpit and chairs toppled and holes punched in the walls, The Atlanta Journal-Constitution reported.
The Rev. Easton Brooks said he would be filing a missing person report on the guard, who his wife identified as Randolph Morgan. He was keeping watch after previous vandalism incidents.
Morgan's cellphone was found in the church.
"I'm very worried," Brooks said. "One of our members was here providing security and as far as we know he's missing. We don't know if he's in danger."
An envelope was found on the floor with the words "Pastor's Love Offering" printed on it, Brooks said. The word "Love" was circled, and under it was written "all of you so much" and "thought you cared for me."
"It's a shame to see how people just have no respect at all for the house of the Lord," the pastor said. "This is where we do the ministry and to see what happened here is beyond belief."