The Senate race was called in Vitter's favor by NBC, which gave him 57 percent of the voted to Melancon's 38 percent.
While running for re-election as a mainstream conservative, Vitter also had his hands full this summer with the impact of the BP oil spill on Louisiana and was a vocal opponent of the federal government's moratorium on offshore drilling permits. He won despite a personal scandal in 2007 in which he apologized publicly after his phone number turned up in the phone records of a prostitution ring in Washington.
Five of the seven House races in Louisiana went to Republicans. A notable exception was in the second district where Democratic state Rep. Cedric Richmond trounced first-term Republican Joseph Cao with 65 percent of the vote to 33 percent.
Two Republican incumbents, Charles Boustany and Rodney Alexander, ran unopposed.