Some protesters shouted "war criminal" as Rove spoke, and Code Pink co-founder Jodie Evans walked toward him with handcuffs, saying she was making a citizen's arrest, a CBS News video showed.
About 10 people protested, among 100 on hand at the Saban Theater Monday as Rove spoke about his new book, "Courage and Consequences: My Life As a Conservative In The Fight," the Los Angeles Times reported.
"Get the heck out of here," Rove told one protester, then referred to him as a "lunatic."
Before being heckled off the stage, Rove said: "With all due respect, this goes to show the totalitarianism of the left. They don't believe in dialogue, they don't believe in the First Amendment."
Rove was unable to sign any audience members' books, the Times said.
Ray Liotta sues skin care company over use of likeness
NBC reportedly holds celebs hostage to Jimmy Fallon's show