Several members of Congress have said they will introduce legislation to repeal the landmark measure, which the House passed Sunday and President Barack Obama is expected to sign Tuesday.
In an interview with Wall Street Journal editors and reporters, Chamber of Commerce President Thomas Donohue was critical of the legislation but said the organization would not commit chamber resources to a repeal effort.
Donohue said the legislation is "very, very expensive" and will disrupt the U.S. healthcare system. The chamber -- which represents an estimated 3 million U.S. businesses -- was a significant player in the campaign against healthcare reform passage.
"If people want to try and repeal, let them," Donohue told the Journal. "We're not going to spend any capital on that."
He said the chamber will try to influence the process in which regulations are developed for enforcement of the new law.
"There's never been a bill this size ever written on anything that doesn't go back for adjustments and refinements," Donohue said.
Notable deaths of 2014 [PHOTOS]