Broward Sheriff Fire Rescue spokesman Mike Jachles said Wednesday's incident at the Broward Correctional Institute began when an inmate stepped on a nest in the jail's recreation yard, the South Florida Sun-Sentinel reported.
In addition to the four people hospitalized after suffering reactions to the bee stings, at least eight other people at the jail were stung in Wednesday's incident.
Jachles said two guards were among those hospitalized but were expected to be released after receiving treatment.
The condition of the two other hospitalized individuals was not reported.
The Sun-Sentinel said the specific type of bees involved in the incident at the detention center remains unknown.