Herenton confirmed Thursday he would step down from his mayoral post effective July 10 so he can focus on his attempt to unseat U.S. Rep. Steve Cohen, D-Tenn., The (Memphis) Commercial-Appeal said.
"This is getting routine for me," Herenton said of his decision. "You don't have the zeal to face it every day, and I'm the kind of guy, I got to climb mountains."
The announcement from Herenton marks the second time the mayor has said he intends to leave his job.
The 69-year-old Memphis politician said on March 20, 2008, he would resign his position, but he eventually remained in place after not taking on the post of schools superintendent.
The Commercial-Appeal said Herenton, who was the first elected black mayor of Memphis, will be replaced as mayor by City Council chairman Myron Lowery. A special election will be held in October to choose the city's next elected mayor.