An unidentified city official told the newspaper a five-agent team arrived last week armed with subpoenas and began collecting data from the city computer system.
A city of New Orleans spokeswoman would not comment on the apparent investigation.
The Times-Picayune said Wednesday it was not clear whether the subpoenas were connected to an investigation involving the allegations that vendors vying for an anti-crime surveillance camera contract made political contributions to Mayor Ray Nagin.
That investigation picked up steam recently when the city's suspended chief technology officer was ordered to testify before a federal grand jury.
Celebrity Couples of 2014 [PHOTOS]