Spokesman James Appathurai said troops will act with Afghan forces "against facilities and facilitators" using drugs to finance the Taliban. Agreement was reached during a meeting of NATO defense ministers in Budapest, the BBC said.
Despite U.S. pressure, several NATO countries have expressed reluctance for a concentrated drug attack, which they say might prompt a violent backlash against allied troops.
Gen. John Craddock, NATO's top operations commander, told alliance members the Afghan opium trade is earning the Taliban insurgency about $100 million a year.
"You cannot have a safe and secure environment with a scourge of narcotics rampant," he said.