Chicago Fire Department spokesman Larry Langford said three people were declared dead at the scene and another man died later at a hospital. A man, a woman and a 2-year-old toddler were listed in critical condition and another man was in stable condition following the accident, the Chicago Tribune said.
Police officials said the driver of the vehicle responsible for the crash had a blood-alcohol level nearly three times the legal limit, the newspaper said.
"It looks like it was a head-on collision but both cars are so mangled that it's hard to tell for sure," Langford told the Tribune.
2014: The Year in Music [PHOTOS]