At least 60 others were wounded by the blast, CNN reported Tuesday.
Investigators say that they found traces of A4 plastic explosive at the site of the blast at Ankara's Ulus shopping center. They describe the explosive as a type often used by the Kurdish Workers Party, or PKK, a separatist group.
Prime Minister Recep Tayyip Erdogan, who visited the scene, described the explosion as a terrorist attack.
"We have to unite against terrorism," Erdogan said. "We have to create a global platform against terrorism."
The blast was in the neighborhood of a bus station at rush hour at a seven-story shopping center in the center of the busy shopping and tourist bazaar.
Four of the dead were Turks and one was a Pakistani national. Some of the injured were also Pakistani.