The eight-hour auction netted nearly $2 million and will help the museum pay for future acquisitions, the Louisville Courier-Journal reported Sunday.
It was the first time the museum had put a portion of its extensive collection up for public auction.
The top price went to a bat used by "Shoeless" Joe Jackson around 1910-1911. The bat was sold for $137,500. Other items sold included bats used by Babe Ruth, Willie Mays, Jim Thorpe, and a Cleveland Indians jersey worn by Satchel Paige.