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EVENTS ON THURSDAY, AUGUST 22, 2002

TIME: All Day

EVENT: NATIONAL INSTITUTES OF HEALTH National Heart, Lung, and Blood Institute, Office of Dietary Supplements and National Center for Complementary and Alternative Medicine hold a conference on Mechanistic Studies of Cardiovascular Effects of Botanicals.

Agenda: Highlights:

8 a.m. - Claude Lenfant, Director, NHLBI

Michael C. Lin, Coordinator, NHLBI

8:30 a.m. - Botanical Medicine: Bridging the Gulf between Promise and Proof

Linda Engel, Acting Director

Division of Extramural Research and Training, NCCAM

NIH Perspectives on Dietary Supplements

Paul Coates, Director, ODS

9:15 a.m. - Development of Botanical Drugs: Regulatory Perspectives on Early Phase Studies

Shaw Chen, U.S. Food and Drug Administration

9:40 a.m. - Garlic

Chair: Eric Block, State University of New York at Albany

Introduction and Overview of the Chemistry and Medicinal Properties of Garlic

Eric Block, State University of New York at Albany

10:10 a.m. - Mechanisms of Cardiovascular Effects of Garlic

Larry Lawson, Plant Bioactives Research Institute

11 a.m. - Effect of Garlic on Biosynthesis and Serum Levels of Cholesterol and Lipids

Rolf Gebhardt, University of Leipzig, Germany

11:30 a.m. - Effect of Garlic on Arteriosclerosis

Gunter Siegel, Free University of Berlin, Germany

1:30 p.m. - Effect of Garlic in Experimental Animal Models

Jose Pedraza-Chaverri, National University of Mexico, Mexico

2 p.m. - Effect of Garlic Powder Tablets on Atherosclerosis

Alexander N. Orekhov, Moskow State University, Russia

2:30 p.m. - Clinical Trials: Efect of Garlic Preparations on Cardiovascular Disease and Its Risk Factors

Christopher Gardner, Stanford University

3 p.m. - Herbal Interactions with Cardiovascular Drugs

Adriane Fugh-Berman, George Washington University

3:30 p.m. - Effect of Steam-distilled Garlic Oil on Cardiovascular Disease

David Maslin, University of Wolverhampton, UK

4:30 p.m. - Ginkgo Biloba

Chair: Curt D. Furberg, Wake Forest University

Vascular Effects of Ginkgo Biloba: Pre-clinical Studies

John Farquhar, Stanford University

5 p.m. - Efficacy of Ginkgo Biloba in the Treatment and Prevention of Cerebrovascular Disease and Cognitive Impairment: The GEM Study

Jeff Williamson, Wake Forest University

DATE: August 22, 2002

LOCATION: Natcher Conference Center, Building 45, Bethesda, MD,

CONTACT: 301-592-3320

WEB ADDRESS:nccam.nih.gov/news/agenda/index.htm

TIME: 8 a.m.

EVENT: FOOD AND DRUG ADMINISTRATION DENTAL PRODUCTS PANEL OF THE MEDICAL DEVICES ADVISORY COMMITTEE holds a meeting to discuss a premarket approval application for a total temporomandibular joint prosthesis for reconstruction of the temporomandibular joint.

DATE: August 22, 2002

LOCATION: Holiday Inn, Walker/Whetstone Rooms, Two Montgomery Village Ave., Gaithersburg, MD.

CONTACT: Pamela D. Scott, 301-827-5283.

WEB ADDRESS: fda.gov

TIME: 6 p.m.

EVENT: SMITHSONIAN Friends of the National Zoo FONZ, presents DJ Steve Bates returning to the Zoo with hits from the '80s. Stop by the Great Ape house to see young Kojo and talk to a keeper.

DATE: August 22, 2002

LOCATION: 3000 Connecticut Avenue NW, Washington, DC

CONTACT: 202-673-4962

WEB ADDRESS: si.edu

TIME: 7 p.m.

EVENT: SMITHSONIAN Art Night performance presents vocal and instrumental quartet Huun-Huur-Tu, on tour from the Tuvan Republic that borders Mongolia, performing their trademark "overtone singing" with accompaniment by Tuvan cello and other instruments, in music rooted in the life of the grasslands and forests of their southern Siberian home.

DATE: August 22, 2002

LOCATION: Hirshhorn Museum and Sculpture Garden, Independence Avenue at Seventh Street SW, Washington, DC

CONTACT: 202-357-3030

WEB ADDRESS: si.edu

TIME: 7 p.m.

EVENT: SMITHSONIAN presents Meet the Artist featuring Doris Salcedo, discussing her work, which responds to the history of violence in Colombia.

DATE: August 22, 2002

LOCATION: Hirshhorn Museum and Sculpture Garden, Independence Avenue at Seventh Street SW, Washington, DC

CONTACT: 202-357-3030

WEB ADDRESS: si.edu