| Scoring Summary |
| First Quarter |
| San Francisco Touchdown - 16-yard pass from J.T. OSullivan to Frank Gore. (Joe Nedney extra point is good). |
| New England Touchdown - 66-yard pass from Matt Cassel to Randy Moss. (Stephen Gostkowski extra point is good). |
| Second Quarter |
| New England Field Goal - 35-yarder by Stephen Gostkowski. |
| New England Touchdown - 2-yard run by Kevin Faulk. (Stephen Gostkowski extra point is good). |
| Third Quarter |
| New England Touchdown - 2-yard run by Kevin Faulk. (Stephen Gostkowski extra point is good). |
|
| Fourth Quarter |
| New England Field Goal - 40-yarder by Stephen Gostkowski. |
| San Francisco Touchdown - 5-yard pass from J.T. OSullivan to Isaac Bruce. (Joe Nedney extra point is good). |
| Individual Statistics |
| Rushing |
| New England |
Sammy Morris 16-63, Kevin Faulk 7-32, Laurence Maroney 10-26, LaMont Jordan 5-16, Matt Cassel 4-5, Randy Moss 1-2 |
| San Francisco |
Frank Gore 12-54, J.T. OSullivan 6-23 |
| Passing |
| New England |
Matt Cassel (22-32), Yards: 259, Sacked: 5, TD: 1 |
| San Francisco |
J.T. OSullivan (14-29), Yards: 130, Sacked: 1, TD: 3 |
| Receiving |
| New England |
Wes Welker 8-73, Randy Moss 5-111, Kevin Faulk 4-29, Jabar Gaffney 3-35, Benjamin Watson 2-11 |
| San Francisco |
Frank Gore 4-24, Isaac Bruce 3-49, Bryant Johnson 3-27, Josh Morgan 2-13, Arnaz Battle 1-9, Delanie Walker 1-8 |
