The three-time All-Star will debut the kicks Thursday in the Pacers' game in London.
"The PG1 is tailored for George's two-way game," according to the Nike website.
The shoes feature a bobber inspired lace lock, a nod to Paul's love of fishing. The low-cut shoes blend "performance innovation with personal details."
The PG1 sock liner features a photo of George from NBA 2K17.
"In Nike's 44-year history, fewer than one percent of its endorsed athletes have been given a signature shoe," according to the Nike website.
"Joining one of the most exclusive clubs in all of sport, Paul George will debut his first signature shoe, the PG1, this week on an international stage as Indiana plays Denver in London on Thursday, January 12," the release said.
George is Nike Basketball's fourth active athlete with a signature shoe. He is the 21st player ever to get a signature shoe from the company.
"Blending George's smooth personality with performance attributes, the PG1 is tailored to PG13's two-way game," according to the Nike release. "The lightweight, low cut PG1 is a true collaboration between George and designer Tony Hardman. The simple, highly functional silhouette features a distinctive forefoot strap anchored by Flywire cable loops providing a dynamic, contained feel, while a forefoot Zoom Air unit delivers low-profile, responsive cushioning."
George is averaging 22.5 points, 6.2 rebounds, and 3.3 assists per game.