Sankey carried the ball 35 times with a touchdown and added three receptions for 63 yards and a score for the Huskies (2-0), who came off a bye week with a victory.
Keith Price went 28-of-35 through the air, amassing 342 yards and two touchdowns.
Jesse Callier picked up 66 yards with a TD on six carries for the Huskies.
Nathan Scheelhaase was held to just 156 passing yards with a touchdown and an interception on 9-of-25 efficiency for the Fighting Illini (2-1). Scheelhaase ran for 21 yards and a TD on 12 carries.