Moore tossed three touchdown passes, and Doug Martin compiled 110 yards and two scores on 22 carries as Broncos (11-1, 6-1 MWC) finished second in the Mountain West Conference to Texas Christian.
Tyler Shoemaker made seven grabs for 106 yards and a touchdown as Coach Chris Petersen became the program's all-time leader with 72 career wins.
The Lobos (1-11, 1-6) managed only 145 passing yards from B.R. Holbrook. Crusoe Gongbay was held to 18 yards on seven carries.